| Date | Away | Home | Time | Winning Pitcher | Losing Pitcher | Winner |
|---|---|---|---|---|---|---|
April | ||||||
| Monday, April 4 | Mariners | @ Rangers | 4:05 pm | Cole Hamels | Felix Hernandez | Rangers |
| Tuesday, April 5 | Mariners | @ Rangers | 8:05 pm | Nick Vincent | Tony Barnette | Mariners |
| Wednesday, April 6 | Mariners | @ Rangers | 2:05 pm | Joaquin Benoit | Shawn Tolleson | Mariners |
| Friday, April 8 | Athletics | @ Mariners | 10:10 pm | Sean Doolittle | Steve Cishek | Athletics |
| Saturday, April 9 | Athletics | @ Mariners | 9:10 pm | Rich Hill | Nathan Karns | Athletics |
| Sunday, April 10 | Athletics | @ Mariners | 4:10 pm | John Axford | Nick Vincent | Athletics |
| Monday, April 11 | Rangers | @ Mariners | 10:10 pm | Colby Lewis | Hisashi Iwakuma | Rangers |
| Tuesday, April 12 | Rangers | @ Mariners | 10:10 pm | Derek Holland | Wade Miley | Rangers |
| Wednesday, April 13 | Rangers | @ Mariners | 3:40 pm | Steve Cishek | Jake Diekman | Mariners |
| Friday, April 15 | Mariners | @ Yankees | 7:05 pm | Nathan Karns | Luis Severino | Mariners |
| Saturday, April 16 | Mariners | @ Yankees | 1:05 pm | Felix Hernandez | CC Sabathia | Mariners |
| Sunday, April 17 | Mariners | @ Yankees | 1:05 pm | Masahiro Tanaka | Hisashi Iwakuma | Yankees |
| Tuesday, April 19 | Mariners | @ Indians | 6:10 pm | Carlos Carrasco | Wade Miley | Indians |
| Wednesday, April 20 | Mariners | @ Indians | 6:10 pm | Taijuan Walker | Danny Salazar | Mariners |
| Thursday, April 21 | Mariners | @ Indians | 12:10 pm | Tony Zych | Cody Allen | Mariners |
| Friday, April 22 | Mariners | @ Angels | 10:05 pm | Joel Peralta | Jose Alvarez | Mariners |
| Saturday, April 23 | Mariners | @ Angels | 9:05 pm | Hector Santiago | Felix Hernandez | Angels |
| Sunday, April 24 | Mariners | @ Angels | 3:35 pm | Wade Miley | Matt Shoemaker | Mariners |
| Monday, April 25 | Astros | @ Mariners | 10:10 pm | Taijuan Walker | Doug Fister | Mariners |
| Tuesday, April 26 | Astros | @ Mariners | 10:10 pm | Nathan Karns | Dallas Keuchel | Mariners |
| Wednesday, April 27 | Astros | @ Mariners | 10:10 pm | Collin McHugh | Hisashi Iwakuma | Astros |
| Friday, April 29 | Royals | @ Mariners | 10:10 pm | Felix Hernandez | Kris Medlen | Mariners |
| Saturday, April 30 | Royals | @ Mariners | 10:10 pm | Wade Miley | Yordano Ventura | Mariners |
May | ||||||
| Sunday, May 1 | Royals | @ Mariners | 4:10 pm | Ian Kennedy | Taijuan Walker | Royals |
| Monday, May 2 | Mariners | @ Athletics | 10:05 pm | Nathan Karns | Kendall Graveman | Mariners |
| Tuesday, May 3 | Mariners | @ Athletics | 10:05 pm | Hisashi Iwakuma | Sonny Gray | Mariners |
| Wednesday, May 4 | Mariners | @ Athletics | 3:35 pm | Mike Montgomery | John Axford | Mariners |
| Thursday, May 5 | Mariners | @ Astros | 8:10 pm | Nick Vincent | Luke Gregerson | Mariners |
| Friday, May 6 | Mariners | @ Astros | 8:10 pm | Doug Fister | Taijuan Walker | Astros |
| Saturday, May 7 | Mariners | @ Astros | 7:10 pm | Steve Cishek | Tony Sipp | Mariners |
| Sunday, May 8 | Mariners | @ Astros | 2:10 pm | Collin McHugh | Hisashi Iwakuma | Astros |
| Monday, May 9 | Rays | @ Mariners | 10:10 pm | Felix Hernandez | Dana Eveland | Mariners |
| Tuesday, May 10 | Rays | @ Mariners | 10:10 pm | Wade Miley | Drew Smyly | Mariners |
| Wednesday, May 11 | Rays | @ Mariners | 3:40 pm | Steve Johnson | Steve Geltz | Mariners |
| Friday, May 13 | Angels | @ Mariners | 10:10 pm | Joe Smith | Steve Cishek | Angels |
| Saturday, May 14 | Angels | @ Mariners | 9:10 pm | Cam Bedrosian | Steve Cishek | Angels |
| Sunday, May 15 | Angels | @ Mariners | 4:10 pm | Hector Santiago | Felix Hernandez | Angels |
| Tuesday, May 17 | Mariners | @ Orioles | 7:05 pm | Wade Miley | Ubaldo Jimenez | Mariners |
| Wednesday, May 18 | Mariners | @ Orioles | 7:05 pm | Chris Tillman | Taijuan Walker | Orioles |
| Thursday, May 19 | Mariners | @ Orioles | 12:35 pm | Nathan Karns | Tyler Wilson | Mariners |
| Friday, May 20 | Mariners | @ Reds | 7:10 pm | Hisashi Iwakuma | Blake Wood | Mariners |
| Saturday, May 21 | Mariners | @ Reds | 4:10 pm | Felix Hernandez | John Lamb | Mariners |
| Sunday, May 22 | Mariners | @ Reds | 1:10 pm | Wade Miley | Alfredo Simon | Mariners |
| Monday, May 23 | Athletics | @ Mariners | 10:10 pm | Rich Hill | Taijuan Walker | Athletics |
| Tuesday, May 24 | Athletics | @ Mariners | 10:10 pm | Mike Montgomery | Ryan Madson | Mariners |
| Wednesday, May 25 | Athletics | @ Mariners | 10:10 pm | Hisashi Iwakuma | Zach Neal | Mariners |
| Friday, May 27 | Twins | @ Mariners | 10:10 pm | Pat Dean | Felix Hernandez | Twins |
| Saturday, May 28 | Twins | @ Mariners | 10:10 pm | Ryan Pressly | Nick Vincent | Twins |
| Sunday, May 29 | Twins | @ Mariners | 4:10 pm | Ricky Nolasco | Taijuan Walker | Twins |
| Monday, May 30 | Padres | @ Mariners | 4:10 pm | Nathan Karns | Andrew Cashner | Mariners |
| Tuesday, May 31 | Padres | @ Mariners | 3:40 pm | Hisashi Iwakuma | James Shields | Mariners |
June | ||||||
| Wednesday, June 1 | Mariners | @ Padres | 10:10 pm | Christian Friedrich | James Paxton | Padres |
| Thursday, June 2 | Mariners | @ Padres | 9:10 pm | Cody Martin | Brandon Maurer | Mariners |
| Friday, June 3 | Mariners | @ Rangers | 8:05 pm | Yu Darvish | Taijuan Walker | Rangers |
| Saturday, June 4 | Mariners | @ Rangers | 9:05 pm | Martin Perez | Nathan Karns | Rangers |
| Sunday, June 5 | Mariners | @ Rangers | 3:05 pm | Derek Holland | Hisashi Iwakuma | Rangers |
| Monday, June 6 | Indians | @ Mariners | 10:10 pm | Trevor Bauer | James Paxton | Indians |
| Tuesday, June 7 | Indians | @ Mariners | 10:10 pm | Wade Miley | Cody Anderson | Mariners |
| Wednesday, June 8 | Indians | @ Mariners | 10:10 pm | Taijuan Walker | Carlos Carrasco | Mariners |
| Thursday, June 9 | Indians | @ Mariners | 10:10 pm | Dan Otero | Joaquin Benoit | Indians |
| Friday, June 10 | Rangers | @ Mariners | 10:10 pm | Hisashi Iwakuma | Derek Holland | Mariners |
| Saturday, June 11 | Rangers | @ Mariners | 10:10 pm | Matt Bush | Mike Montgomery | Rangers |
| Sunday, June 12 | Rangers | @ Mariners | 4:10 pm | Cole Hamels | Wade Miley | Rangers |
| Tuesday, June 14 | Mariners | @ Rays | 7:10 pm | Ryan Garton | Mike Montgomery | Rays |
| Wednesday, June 15 | Mariners | @ Rays | 7:10 pm | Matt Andriese | Mike Montgomery | Rays |
| Thursday, June 16 | Mariners | @ Rays | 1:10 pm | James Paxton | Blake Snell | Mariners |
| Friday, June 17 | Mariners | @ Red Sox | 7:10 pm | Hisashi Iwakuma | Roenis Elias | Mariners |
| Saturday, June 18 | Mariners | @ Red Sox | 4:05 pm | Rick Porcello | Adrian Sampson | Red Sox |
| Sunday, June 19 | Mariners | @ Red Sox | 1:35 pm | David Price | Edwin Diaz | Red Sox |
| Monday, June 20 | Mariners | @ Tigers | 7:10 pm | Anibal Sanchez | Vidal Nuno | Tigers |
| Tuesday, June 21 | Mariners | @ Tigers | 7:10 pm | Bruce Rondon | James Paxton | Tigers |
| Wednesday, June 22 | Mariners | @ Tigers | 7:10 pm | Kyle Ryan | Hisashi Iwakuma | Tigers |
| Thursday, June 23 | Mariners | @ Tigers | 1:10 pm | Kyle Ryan | Steve Cishek | Tigers |
| Friday, June 24 | Cardinals | @ Mariners | 10:10 pm | Donn Roach | Trevor Rosenthal | Mariners |
| Saturday, June 25 | Cardinals | @ Mariners | 10:10 pm | Nathan Karns | Mike Leake | Mariners |
| Sunday, June 26 | Cardinals | @ Mariners | 4:10 pm | Kevin Siegrist | Nick Vincent | Cardinals |
| Tuesday, June 28 | Pirates | @ Mariners | 10:10 pm | Hisashi Iwakuma | Jonathon Niese | Mariners |
| Wednesday, June 29 | Pirates | @ Mariners | 10:10 pm | Jameson Taillon | Wade Miley | Pirates |
| Thursday, June 30 | Orioles | @ Mariners | 10:10 pm | Taijuan Walker | Chris Tillman | Mariners |
July | ||||||
| Friday, July 1 | Orioles | @ Mariners | 10:10 pm | Wade LeBlanc | Kevin Gausman | Mariners |
| Saturday, July 2 | Orioles | @ Mariners | 10:10 pm | James Paxton | Tyler Wilson | Mariners |
| Sunday, July 3 | Orioles | @ Mariners | 4:10 pm | Hisashi Iwakuma | Ubaldo Jimenez | Mariners |
| Monday, July 4 | Mariners | @ Astros | 2:10 pm | Lance McCullers Jr. | Wade Miley | Astros |
| Tuesday, July 5 | Mariners | @ Astros | 8:10 pm | Dallas Keuchel | Taijuan Walker | Astros |
| Wednesday, July 6 | Mariners | @ Astros | 8:10 pm | Ken Giles | Edwin Diaz | Astros |
| Thursday, July 7 | Mariners | @ Royals | 8:15 pm | Brooks Pounders | Steve Cishek | Royals |
| Friday, July 8 | Mariners | @ Royals | 8:15 pm | Hisashi Iwakuma | Yordano Ventura | Mariners |
| Saturday, July 9 | Mariners | @ Royals | 4:15 pm | Edinson Volquez | Wade Miley | Royals |
| Sunday, July 10 | Mariners | @ Royals | 2:15 pm | Mike Montgomery | Dillon Gee | Mariners |
| Friday, July 15 | Astros | @ Mariners | 10:10 pm | Doug Fister | James Paxton | Astros |
| Saturday, July 16 | Astros | @ Mariners | 4:10 pm | Hisashi Iwakuma | Lance McCullers Jr. | Mariners |
| Sunday, July 17 | Astros | @ Mariners | 4:10 pm | Collin McHugh | Mike Montgomery | Astros |
| Monday, July 18 | White Sox | @ Mariners | 10:10 pm | David Rollins | David Robertson | Mariners |
| Tuesday, July 19 | White Sox | @ Mariners | 10:10 pm | Jose Quintana | Wade Miley | White Sox |
| Wednesday, July 20 | White Sox | @ Mariners | 3:40 pm | Vidal Nuno | Dan Jennings | Mariners |
| Friday, July 22 | Mariners | @ Blue Jays | 7:07 pm | James Paxton | Marco Estrada | Mariners |
| Saturday, July 23 | Mariners | @ Blue Jays | 1:07 pm | Hisashi Iwakuma | R.A. Dickey | Mariners |
| Sunday, July 24 | Mariners | @ Blue Jays | 1:07 pm | J.A. Happ | Wade Miley | Blue Jays |
| Tuesday, July 26 | Mariners | @ Pirates | 7:05 pm | Felix Hernandez | Francisco Liriano | Mariners |
| Wednesday, July 27 | Mariners | @ Pirates | 7:05 pm | Gerrit Cole | James Paxton | Pirates |
| Friday, July 29 | Mariners | @ Cubs | 2:20 pm | Jon Lester | Hisashi Iwakuma | Cubs |
| Saturday, July 30 | Mariners | @ Cubs | 2:20 pm | Wade Miley | Jake Arrieta | Mariners |
| Sunday, July 31 | Mariners | @ Cubs | 8:08 pm | Hector Rondon | Cody Martin | Cubs |
August | ||||||
| Monday, August 1 | Red Sox | @ Mariners | 10:10 pm | Junichi Tazawa | Steve Cishek | Red Sox |
| Tuesday, August 2 | Red Sox | @ Mariners | 10:10 pm | Donn Roach | Fernando Abad | Mariners |
| Wednesday, August 3 | Red Sox | @ Mariners | 10:10 pm | Hisashi Iwakuma | Rick Porcello | Mariners |
| Thursday, August 4 | Red Sox | @ Mariners | 10:10 pm | Craig Kimbrel | Cody Martin | Red Sox |
| Friday, August 5 | Angels | @ Mariners | 10:10 pm | Felix Hernandez | Tim Lincecum | Mariners |
| Saturday, August 6 | Angels | @ Mariners | 9:10 pm | Drew Storen | Jose Valdez | Mariners |
| Sunday, August 7 | Angels | @ Mariners | 4:10 pm | James Paxton | Matt Shoemaker | Mariners |
| Monday, August 8 | Tigers | @ Mariners | 10:10 pm | Hisashi Iwakuma | Michael Fulmer | Mariners |
| Tuesday, August 9 | Tigers | @ Mariners | 10:10 pm | Ariel Miranda | Francisco Rodriguez | Mariners |
| Wednesday, August 10 | Tigers | @ Mariners | 10:10 pm | Arquimedes Caminero | Justin Wilson | Mariners |
| Friday, August 12 | Mariners | @ Athletics | 10:05 pm | Sean Manaea | Joe Wieland | Athletics |
| Saturday, August 13 | Mariners | @ Athletics | 9:05 pm | Hisashi Iwakuma | Kendall Graveman | Mariners |
| Sunday, August 14 | Mariners | @ Athletics | 4:05 pm | Wade LeBlanc | Zach Neal | Mariners |
| Monday, August 15 | Mariners | @ Angels | 10:05 pm | Felix Hernandez | Ricky Nolasco | Mariners |
| Tuesday, August 16 | Mariners | @ Angels | 10:05 pm | Brett Oberholtzer | Arquimedes Caminero | Angels |
| Wednesday, August 17 | Mariners | @ Angels | 10:05 pm | Drew Storen | Tyler Skaggs | Mariners |
| Thursday, August 18 | Mariners | @ Angels | 10:05 pm | Matt Shoemaker | Hisashi Iwakuma | Angels |
| Friday, August 19 | Brewers | @ Mariners | 10:10 pm | Wade LeBlanc | Brent Suter | Mariners |
| Saturday, August 20 | Brewers | @ Mariners | 9:10 pm | Felix Hernandez | Wily Peralta | Mariners |
| Sunday, August 21 | Brewers | @ Mariners | 4:10 pm | Tyler Thornburg | Tom Wilhelmsen | Brewers |
| Monday, August 22 | Yankees | @ Mariners | 10:10 pm | Nick Vincent | Anthony Swarzak | Mariners |
| Tuesday, August 23 | Yankees | @ Mariners | 10:10 pm | CC Sabathia | Taijuan Walker | Yankees |
| Wednesday, August 24 | Yankees | @ Mariners | 3:40 pm | Masahiro Tanaka | Hisashi Iwakuma | Yankees |
| Thursday, August 25 | Mariners | @ White Sox | 8:10 pm | David Robertson | Nick Vincent | White Sox |
| Friday, August 26 | Mariners | @ White Sox | 8:10 pm | Felix Hernandez | Chris Sale | Mariners |
| Saturday, August 27 | Mariners | @ White Sox | 7:10 pm | Jose Quintana | Ariel Miranda | White Sox |
| Sunday, August 28 | Mariners | @ White Sox | 2:10 pm | Carlos Rodon | Taijuan Walker | White Sox |
| Monday, August 29 | Mariners | @ Rangers | 8:05 pm | Yu Darvish | Hisashi Iwakuma | Rangers |
| Tuesday, August 30 | Mariners | @ Rangers | 8:05 pm | Matt Bush | Edwin Diaz | Rangers |
| Wednesday, August 31 | Mariners | @ Rangers | 2:05 pm | Martin Perez | Felix Hernandez | Rangers |
September | ||||||
| Friday, September 2 | Angels | @ Mariners | 10:10 pm | Ariel Miranda | Brett Oberholtzer | Mariners |
| Saturday, September 3 | Angels | @ Mariners | 9:10 pm | Tyler Skaggs | Taijuan Walker | Angels |
| Sunday, September 4 | Angels | @ Mariners | 4:10 pm | Deolis Guerra | Hisashi Iwakuma | Angels |
| Monday, September 5 | Rangers | @ Mariners | 4:10 pm | Felix Hernandez | Cole Hamels | Mariners |
| Tuesday, September 6 | Rangers | @ Mariners | 10:10 pm | Martin Perez | James Paxton | Rangers |
| Wednesday, September 7 | Rangers | @ Mariners | 10:10 pm | Ariel Miranda | A.J. Griffin | Mariners |
| Thursday, September 8 | Rangers | @ Mariners | 10:10 pm | Taijuan Walker | Derek Holland | Mariners |
| Friday, September 9 | Mariners | @ Athletics | 10:05 pm | Hisashi Iwakuma | Daniel Mengden | Mariners |
| Saturday, September 10 | Mariners | @ Athletics | 4:05 pm | Felix Hernandez | Kendall Graveman | Mariners |
| Sunday, September 11 | Mariners | @ Athletics | 4:05 pm | Steve Cishek | Ryan Madson | Mariners |
| Monday, September 12 | Mariners | @ Angels | 10:05 pm | Ariel Miranda | Ricky Nolasco | Mariners |
| Tuesday, September 13 | Mariners | @ Angels | 10:05 pm | Taijuan Walker | Alex Meyer | Mariners |
| Wednesday, September 14 | Mariners | @ Angels | 10:05 pm | Hisashi Iwakuma | Jose Valdez | Mariners |
| Friday, September 16 | Astros | @ Mariners | 10:10 pm | Collin McHugh | Felix Hernandez | Astros |
| Saturday, September 17 | Astros | @ Mariners | 9:10 pm | Mike Fiers | James Paxton | Astros |
| Sunday, September 18 | Astros | @ Mariners | 4:10 pm | Ariel Miranda | Doug Fister | Mariners |
| Monday, September 19 | Blue Jays | @ Mariners | 10:10 pm | Marco Estrada | Taijuan Walker | Blue Jays |
| Tuesday, September 20 | Blue Jays | @ Mariners | 10:10 pm | J.A. Happ | Hisashi Iwakuma | Blue Jays |
| Wednesday, September 21 | Blue Jays | @ Mariners | 3:40 pm | Nick Vincent | R.A. Dickey | Mariners |
| Friday, September 23 | Mariners | @ Twins | 8:10 pm | James Paxton | Kyle Gibson | Mariners |
| Saturday, September 24 | Mariners | @ Twins | 7:10 pm | Tyler Duffey | Ariel Miranda | Twins |
| Sunday, September 25 | Mariners | @ Twins | 2:10 pm | Taijuan Walker | Hector Santiago | Mariners |
| Monday, September 26 | Mariners | @ Astros | 8:10 pm | Drew Storen | Luke Gregerson | Mariners |
| Tuesday, September 27 | Mariners | @ Astros | 8:10 pm | Jandel Gustave | Felix Hernandez | Astros |
| Wednesday, September 28 | Mariners | @ Astros | 2:10 pm | James Paxton | Doug Fister | Mariners |
| Thursday, September 29 | Athletics | @ Mariners | 10:10 pm | Steve Cishek | Liam Hendriks | Mariners |
| Friday, September 30 | Athletics | @ Mariners | 10:10 pm | Taijuan Walker | Raul Alcantara | Mariners |
October | ||||||
| Saturday, October 1 | Athletics | @ Mariners | 9:10 pm | Ryan Madson | Edwin Diaz | Athletics |
| Sunday, October 2 | Athletics | @ Mariners | 3:10 pm | Sean Manaea | Felix Hernandez | Athletics |
April | ||||||
| Monday, April 3 | Mariners | @ Astros | 8:10 pm | - | ||
| Tuesday, April 4 | Mariners | @ Astros | 8:10 pm | - | ||
| Wednesday, April 5 | Mariners | @ Astros | 8:10 pm | - | ||
| Thursday, April 6 | Mariners | @ Astros | 8:10 pm | - | ||
| Friday, April 7 | Mariners | @ Angels | 10:07 pm | - | ||
| Saturday, April 8 | Mariners | @ Angels | 10:07 pm | - | ||
| Sunday, April 9 | Mariners | @ Angels | 3:37 pm | - | ||
| Monday, April 10 | Astros | @ Mariners | 5:10 pm | - | ||
| Tuesday, April 11 | Astros | @ Mariners | 10:10 pm | - | ||
| Wednesday, April 12 | Astros | @ Mariners | 10:10 pm | - | ||
| Friday, April 14 | Rangers | @ Mariners | 10:10 pm | - | ||
| Saturday, April 15 | Rangers | @ Mariners | 9:10 pm | - | ||
| Sunday, April 16 | Rangers | @ Mariners | 4:10 pm | - | ||
| Monday, April 17 | Marlins | @ Mariners | 10:10 pm | - | ||
| Tuesday, April 18 | Marlins | @ Mariners | 10:10 pm | - | ||
| Wednesday, April 19 | Marlins | @ Mariners | 3:40 pm | - | ||
| Thursday, April 20 | Mariners | @ Athletics | 10:05 pm | - | ||
| Friday, April 21 | Mariners | @ Athletics | 10:05 pm | - | ||
| Saturday, April 22 | Mariners | @ Athletics | 4:05 pm | - | ||
| Sunday, April 23 | Mariners | @ Athletics | 4:05 pm | - | ||
| Tuesday, April 25 | Mariners | @ Tigers | 7:10 pm | - | ||
| Wednesday, April 26 | Mariners | @ Tigers | 7:10 pm | - | ||
| Thursday, April 27 | Mariners | @ Tigers | 1:10 pm | - | ||
| Friday, April 28 | Mariners | @ Indians | 7:10 pm | - | ||
| Saturday, April 29 | Mariners | @ Indians | 4:10 pm | - | ||
| Sunday, April 30 | Mariners | @ Indians | 1:10 pm | - | ||
May | ||||||
| Tuesday, May 2 | Angels | @ Mariners | 10:10 pm | - | ||
| Wednesday, May 3 | Angels | @ Mariners | 10:10 pm | - | ||
| Thursday, May 4 | Angels | @ Mariners | 10:10 pm | - | ||
| Friday, May 5 | Rangers | @ Mariners | 10:10 pm | - | ||
| Saturday, May 6 | Rangers | @ Mariners | 9:10 pm | - | ||
| Sunday, May 7 | Rangers | @ Mariners | 4:10 pm | - | ||
| Tuesday, May 9 | Mariners | @ Phillies | 7:05 pm | - | ||
| Wednesday, May 10 | Mariners | @ Phillies | 1:05 pm | - | ||
| Thursday, May 11 | Mariners | @ Blue Jays | 7:07 pm | - | ||
| Friday, May 12 | Mariners | @ Blue Jays | 7:07 pm | - | ||
| Saturday, May 13 | Mariners | @ Blue Jays | 1:07 pm | - | ||
| Sunday, May 14 | Mariners | @ Blue Jays | 1:07 pm | - | ||
| Monday, May 15 | Athletics | @ Mariners | 10:10 pm | - | ||
| Tuesday, May 16 | Athletics | @ Mariners | 10:10 pm | - | ||
| Wednesday, May 17 | Athletics | @ Mariners | 10:10 pm | - | ||
| Thursday, May 18 | White Sox | @ Mariners | 10:10 pm | - | ||
| Friday, May 19 | White Sox | @ Mariners | 10:10 pm | - | ||
| Saturday, May 20 | White Sox | @ Mariners | 10:10 pm | - | ||
| Sunday, May 21 | White Sox | @ Mariners | 4:10 pm | - | ||
| Tuesday, May 23 | Mariners | @ Nationals | 7:05 pm | - | ||
| Wednesday, May 24 | Mariners | @ Nationals | 7:05 pm | - | ||
| Thursday, May 25 | Mariners | @ Nationals | 4:05 pm | - | ||
| Friday, May 26 | Mariners | @ Red Sox | 7:10 pm | - | ||
| Saturday, May 27 | Mariners | @ Red Sox | 4:05 pm | - | ||
| Sunday, May 28 | Mariners | @ Red Sox | 1:35 pm | - | ||
| Monday, May 29 | Mariners | @ Rockies | 3:10 pm | - | ||
| Tuesday, May 30 | Mariners | @ Rockies | 7:10 pm | - | ||
| Wednesday, May 31 | Rockies | @ Mariners | 10:10 pm | - | ||
June | ||||||
| Thursday, June 1 | Rockies | @ Mariners | 3:40 pm | - | ||
| Friday, June 2 | Rays | @ Mariners | 10:10 pm | - | ||
| Saturday, June 3 | Rays | @ Mariners | 10:10 pm | - | ||
| Sunday, June 4 | Rays | @ Mariners | 4:10 pm | - | ||
| Tuesday, June 6 | Twins | @ Mariners | 10:10 pm | - | ||
| Wednesday, June 7 | Twins | @ Mariners | 10:10 pm | - | ||
| Thursday, June 8 | Twins | @ Mariners | 10:10 pm | - | ||
| Friday, June 9 | Blue Jays | @ Mariners | 10:10 pm | - | ||
| Saturday, June 10 | Blue Jays | @ Mariners | 10:10 pm | - | ||
| Sunday, June 11 | Blue Jays | @ Mariners | 4:10 pm | - | ||
| Monday, June 12 | Mariners | @ Twins | 8:10 pm | - | ||
| Tuesday, June 13 | Mariners | @ Twins | 8:10 pm | - | ||
| Wednesday, June 14 | Mariners | @ Twins | 8:10 pm | - | ||
| Thursday, June 15 | Mariners | @ Twins | 1:10 pm | - | ||
| Friday, June 16 | Mariners | @ Rangers | 8:05 pm | - | ||
| Saturday, June 17 | Mariners | @ Rangers | 5:05 pm | - | ||
| Sunday, June 18 | Mariners | @ Rangers | 3:05 pm | - | ||
| Monday, June 19 | Tigers | @ Mariners | 10:10 pm | - | ||
| Tuesday, June 20 | Tigers | @ Mariners | 10:10 pm | - | ||
| Wednesday, June 21 | Tigers | @ Mariners | 10:10 pm | - | ||
| Thursday, June 22 | Tigers | @ Mariners | 10:10 pm | - | ||
| Friday, June 23 | Astros | @ Mariners | 10:10 pm | - | ||
| Saturday, June 24 | Astros | @ Mariners | 10:10 pm | - | ||
| Sunday, June 25 | Astros | @ Mariners | 4:10 pm | - | ||
| Tuesday, June 27 | Phillies | @ Mariners | 10:10 pm | - | ||
| Wednesday, June 28 | Phillies | @ Mariners | 3:40 pm | - | ||
| Friday, June 30 | Mariners | @ Angels | 10:07 pm | - | ||
July | ||||||
| Saturday, July 1 | Mariners | @ Angels | 10:07 pm | - | ||
| Sunday, July 2 | Mariners | @ Angels | 3:37 pm | - | ||
| Monday, July 3 | Royals | @ Mariners | 10:10 pm | - | ||
| Tuesday, July 4 | Royals | @ Mariners | 6:40 pm | - | ||
| Wednesday, July 5 | Royals | @ Mariners | 10:10 pm | - | ||
| Thursday, July 6 | Athletics | @ Mariners | 10:10 pm | - | ||
| Friday, July 7 | Athletics | @ Mariners | 10:10 pm | - | ||
| Saturday, July 8 | Athletics | @ Mariners | 10:10 pm | - | ||
| Sunday, July 9 | Athletics | @ Mariners | 4:10 pm | - | ||
| Friday, July 14 | Mariners | @ White Sox | 8:10 pm | - | ||
| Saturday, July 15 | Mariners | @ White Sox | 7:10 pm | - | ||
| Sunday, July 16 | Mariners | @ White Sox | 2:10 pm | - | ||
| Monday, July 17 | Mariners | @ Astros | 8:10 pm | - | ||
| Tuesday, July 18 | Mariners | @ Astros | 8:10 pm | - | ||
| Wednesday, July 19 | Mariners | @ Astros | 2:10 pm | - | ||
| Thursday, July 20 | Yankees | @ Mariners | 10:10 pm | - | ||
| Friday, July 21 | Yankees | @ Mariners | 10:10 pm | - | ||
| Saturday, July 22 | Yankees | @ Mariners | 9:10 pm | - | ||
| Sunday, July 23 | Yankees | @ Mariners | 4:10 pm | - | ||
| Monday, July 24 | Red Sox | @ Mariners | 10:10 pm | - | ||
| Tuesday, July 25 | Red Sox | @ Mariners | 10:10 pm | - | ||
| Wednesday, July 26 | Red Sox | @ Mariners | 3:40 pm | - | ||
| Friday, July 28 | Mets | @ Mariners | 10:10 pm | - | ||
| Saturday, July 29 | Mets | @ Mariners | 4:10 pm | - | ||
| Sunday, July 30 | Mets | @ Mariners | 4:10 pm | - | ||
| Monday, July 31 | Mariners | @ Rangers | 8:05 pm | - | ||
August | ||||||
| Tuesday, August 1 | Mariners | @ Rangers | 8:05 pm | - | ||
| Wednesday, August 2 | Mariners | @ Rangers | 8:05 pm | - | ||
| Thursday, August 3 | Mariners | @ Royals | 8:15 pm | - | ||
| Friday, August 4 | Mariners | @ Royals | 8:15 pm | - | ||
| Saturday, August 5 | Mariners | @ Royals | 7:15 pm | - | ||
| Sunday, August 6 | Mariners | @ Royals | 2:15 pm | - | ||
| Tuesday, August 8 | Mariners | @ Athletics | 10:05 pm | - | ||
| Wednesday, August 9 | Mariners | @ Athletics | 3:35 pm | - | ||
| Thursday, August 10 | Angels | @ Mariners | 10:10 pm | - | ||
| Friday, August 11 | Angels | @ Mariners | 10:10 pm | - | ||
| Saturday, August 12 | Angels | @ Mariners | 9:10 pm | - | ||
| Sunday, August 13 | Angels | @ Mariners | 4:10 pm | - | ||
| Monday, August 14 | Orioles | @ Mariners | 10:10 pm | - | ||
| Tuesday, August 15 | Orioles | @ Mariners | 10:10 pm | - | ||
| Wednesday, August 16 | Orioles | @ Mariners | 3:40 pm | - | ||
| Friday, August 18 | Mariners | @ Rays | 7:10 pm | - | ||
| Saturday, August 19 | Mariners | @ Rays | 6:10 pm | - | ||
| Sunday, August 20 | Mariners | @ Rays | 1:10 pm | - | ||
| Monday, August 21 | Mariners | @ Braves | 7:35 pm | - | ||
| Tuesday, August 22 | Mariners | @ Braves | 7:35 pm | - | ||
| Wednesday, August 23 | Mariners | @ Braves | 7:35 pm | - | ||
| Friday, August 25 | Mariners | @ Yankees | 7:05 pm | - | ||
| Saturday, August 26 | Mariners | @ Yankees | 1:05 pm | - | ||
| Sunday, August 27 | Mariners | @ Yankees | 1:05 pm | - | ||
| Monday, August 28 | Mariners | @ Orioles | 7:05 pm | - | ||
| Tuesday, August 29 | Mariners | @ Orioles | 7:05 pm | - | ||
| Wednesday, August 30 | Mariners | @ Orioles | 3:05 pm | - | ||
September | ||||||
| Friday, September 1 | Athletics | @ Mariners | 10:10 pm | - | ||
| Saturday, September 2 | Athletics | @ Mariners | 9:10 pm | - | ||
| Sunday, September 3 | Athletics | @ Mariners | 4:10 pm | - | ||
| Monday, September 4 | Astros | @ Mariners | 6:40 pm | - | ||
| Tuesday, September 5 | Astros | @ Mariners | 10:10 pm | - | ||
| Wednesday, September 6 | Astros | @ Mariners | 10:10 pm | - | ||
| Friday, September 8 | Angels | @ Mariners | 10:10 pm | - | ||
| Saturday, September 9 | Angels | @ Mariners | 9:10 pm | - | ||
| Sunday, September 10 | Angels | @ Mariners | 4:10 pm | - | ||
| Monday, September 11 | Mariners | @ Rangers | 8:05 pm | - | ||
| Tuesday, September 12 | Mariners | @ Rangers | 8:05 pm | - | ||
| Wednesday, September 13 | Mariners | @ Rangers | 8:05 pm | - | ||
| Thursday, September 14 | Mariners | @ Rangers | 8:05 pm | - | ||
| Friday, September 15 | Mariners | @ Astros | 8:10 pm | - | ||
| Saturday, September 16 | Mariners | @ Astros | 7:10 pm | - | ||
| Sunday, September 17 | Mariners | @ Astros | 2:10 pm | - | ||
| Tuesday, September 19 | Rangers | @ Mariners | 10:10 pm | - | ||
| Wednesday, September 20 | Rangers | @ Mariners | 10:10 pm | - | ||
| Thursday, September 21 | Rangers | @ Mariners | 10:10 pm | - | ||
| Friday, September 22 | Indians | @ Mariners | 10:10 pm | - | ||
| Saturday, September 23 | Indians | @ Mariners | 4:10 pm | - | ||
| Sunday, September 24 | Indians | @ Mariners | 4:10 pm | - | ||
| Monday, September 25 | Mariners | @ Athletics | 10:05 pm | - | ||
| Tuesday, September 26 | Mariners | @ Athletics | 10:05 pm | - | ||
| Wednesday, September 27 | Mariners | @ Athletics | 3:35 pm | - | ||
| Friday, September 29 | Mariners | @ Angels | 10:07 pm | - | ||
| Saturday, September 30 | Mariners | @ Angels | 9:07 pm | - | ||
October | ||||||
| Sunday, October 1 | Mariners | @ Angels | 3:07 pm | - | ||